Nitrazepam has been related to extreme hepatic Diseases, comparable to other nitrobenzodiazepines. Nitrobenzodiazepines which include nitrazepam, nimetazepam, flunitrazepam, and clonazepam tend to be more harmful to your liver than other benzodiazepines as They are really metabolically activated by CYP3A4 which may lead to cytotoxicity.[thirty] Cau